Tumor Marker Carbohydrate Antigen 724(CA72-4 )detection kit based in the diagnosis
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Tumor Marker Carbohydrate Antigen 724(CA72-4 )detection kit based in the diagnosis

Cancer antigen 72-4 (CA 72-4), which is also known as carbohydrate antigen, is identified as a serum tumor biomarker (threshold of approximately 4.6 U/mL in serum), which allows the suspicion of cancer. CA 72-4 is an antigenic determinant of tumor-associated glycoprotein 72 (TAG-72) glycoprotein, which is a 48-kDa mucin-like glycoprotein complex. CA 72-4 is defined by two monoclonal antibodies (CC 49 and B72-3) and has been found in a wide range of human adenocarcinomas such as colorectal, gastric, lung, breast, and ovarian cancer, with reported sensitivities of up 50% and an overall specificity of over 95%. However, it is rarely expressed in benign and normal adult tissues. Measurement of CA 72-4 has also shown good correlation with disease burden and is predictive of disease recurrence.
  • CA72-4

  • zecen

  • DR1055

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Cancer antigen 72-4 (CA72-4) is a tumor-associated-glycoprotein (TAG-72) used as a tumor marker for gastrointestinal and ovarian cancers. Elevated CA72-4 levels in serum and plasma are seen in the pancreas, gallbladder, colon, cervix, and endometrium carcinomas. There is a correlation between serum CA72-4 levels and tumor stage/size compared to other commonly used biomarkers. CA72-4 is also an independent marker for the therapeutic monitoring and care of ovarian cancer patients who are CA125 negative.











[INTENDED USE]


The kit has been designed for the quantitative determination of Carbohydrate antigen 72-4 (CA72-4) in human serum.

The method can be used for samples over the range of 0-200U/mL



The method can be used for samples over the range of 0-200U/mL.The test has to be performed on the CIA fully auto analyzer (Including CIA 600, CIA 1200, CIA 1800, CIA2800).

 

[KIT COMPONENTS]


Material Supplies

Reagent Integral for 100 determinations
Magnetic beads: magnetic beads binding with streptavidin, buffer with BSA3.0ml
Calibrator Low: BSA Buffer0.6ml
Calibrator High: BSA Buffer0.6ml
CA72-4 Anti A+ Anti B: CA72-4 Antibody labeled by biotin,BSA Buffer;CA72-4 Antibody complex labeled by AP, containing buffer with BSA6.0ml
All reagents are provided ready-to-use.

 

 

Reagent Vials in kit box

Internal Quality Control: containing BSA buffer with different amount of CA72-4 Antigen

(target value refer to Quality Control sheet)

0.3ml

 

Accessories Required But Not Provided

CIA SubstrateREF: SR2001
CIA System cleaning solutionREF: WR2001
CIA Pileline cleaning solutionREF: WR2002


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Zecen Biotech CO., LTD. founded in 2011, is a leading Chinese diagnostics manufacturer specializing in in-vitro diagnostics devices and reagents.
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